Sein Vater Jakob VI. war sehr eifersüchtig auf die Beliebtheit seines Sohnes Henry Frederik.
"In person he [Henry Frederik] was tall, being more than six feet high [also größer als 1,83 m] when he reached his seventeenth year; he was large-boned, thin skinned, fair in complexion, and with a Grecian cast of features. He injured his health by long bathing after supper, by taking violent exercise during the greatest heats of summer, by recklessly exposing himself to the storms and rains of winter, and by indulging too freely in the luxuries of the table. In the spring of 1612, his health and spirits began to decline; during the summer he grew worse; as September drew to a close, he, on returning from his sports in the country, became alarmingly ill, and on reaching St. James’s was attacked with an intermittent fever … The Queen, hitherto, had watched at the bedside of her unfortunate son; but immediately the malignant symptoms became evident, a dread of infection forced her to retire to her own palace of Somerset-house … She remembered that Sir Walter Raleigh had a quack medicine, which she had herself taken with success for an ague. For this nostrum she accordingly sent, in the hope of restoring her son to health. Sir Walter, who deeply lamented the Prince’s danger, had full faith in the medicine, and with a large packet of it which had been carefully prepared for the purpose by his own hands, sent word, that, 'with the exception of poison, it would cure all mortal diseases.' The Prince swallowed a dose, revived for a short while, and then, about half-past seven in the evening of the sixth of November, 1612, breathed his last. … The body of the Prince was opened, and the still existing report of the surgeons, who made the post-mortem examination, render it evident that he died of a malignant fever." (in: Francis Lancelott: The Queens of England and their Times, Volume II, id., p. 671).